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Picayune, Mississippi Hotels and City Guide

Picayune Hotels and Picayune Guide with Picayune maps, top attractions, room reservations and hotel deals at a wide range of the best Picayune hotels

Hotels in Picayune, Mississippi

Comfort Inn Picayune

Comfort Inn Picayune

550 South Lofton Dr. Picayune Mississippi USA

Within 2 miles of historic district and antique shops. Within 1 hour of New Orleans, LA and Gulfport casinos.




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Days Inn - Picayune

Days Inn - Picayune

450 South Lofton Ave., Picayune, 39466

Pride of PicayuneBrand new FacilityBeautifully decorated deluxe smoking and Nonsmoking roomsHandicapped RoomsCrib /Rollaway Available24HR front desk serviceFree Continental BreakfastMicrowave,Refrigerator,Hairdryer,and...




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